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clec-196 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178506, updated on 9-Dec-2024

Summary

Official Symbol
clec-196
Official Full Name
C-type lectin domain-containing protein
Primary source
WormBase:WBGene00009156
Locus tag
CELE_F26D10.12
See related
AllianceGenome:WB:WBGene00009156
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Orthologous to several human genes including CLEC7A (C-type lectin domain containing 7A). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See clec-196 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (17276956..17277748)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene glutamine synthetase Neighboring gene Lipoma HMGIC fusion partner-like 3 protein Neighboring gene ncRNA Neighboring gene Heat shock protein hsp-1 Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables pattern recognition receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
C-type lectin domain-containing protein
NP_001255932.1
  • Confirmed by transcript evidence
NP_001255933.1
  • Confirmed by transcript evidence
NP_001299955.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    17276956..17277748
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269003.2NP_001255932.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255932.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XVT9
    Conserved Domains (1) summary
    smart00034
    Location:29142
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
  2. NM_001313026.3NP_001299955.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3ARI7
  3. NM_001269004.3NP_001255933.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255933.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F5GUE2