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sta-1 Signal transducer and activator of transcription 1 [ Caenorhabditis elegans ]

Gene ID: 178465, updated on 28-Oct-2021

Summary

Gene symbol
sta-1
Gene description
Signal transducer and activator of transcription 1
Primary source
WormBase:WBGene00013111
Locus tag
CELE_Y51H4A.17
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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Genomic context

See sta-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
8
Sequence:
Chromosome: IV; NC_003282.8 (16664320..16671472)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene ncRNA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in dauer larval development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in dauer larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in defense response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in receptor signaling pathway via JAK-STAT IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Signal transducer and activator of transcription 1
NP_001122814.1
  • Confirmed by transcript evidence
NP_001122815.1
  • Confirmed by transcript evidence
NP_502974.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    16664320..16671472
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070573.6NP_502974.2  Signal transducer and activator of transcription 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502974.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9NAD6
    Conserved Domains (3) summary
    cd09919
    Location:457574
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    pfam01017
    Location:7196
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:199466
    STAT_bind; STAT protein, DNA binding domain
  2. NM_001129343.3NP_001122815.1  Signal transducer and activator of transcription 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122815.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9NAD6
    Conserved Domains (3) summary
    cd09919
    Location:457574
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    pfam01017
    Location:7196
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:199466
    STAT_bind; STAT protein, DNA binding domain
  3. NM_001129342.4NP_001122814.1  Signal transducer and activator of transcription 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122814.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9NAD6
    Conserved Domains (3) summary
    cd09919
    Location:457553
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    pfam01017
    Location:7196
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:199466
    STAT_bind; STAT protein, DNA binding domain
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