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qars-1 Probable glutamine--tRNA ligase [ Caenorhabditis elegans ]

Gene ID: 178415, updated on 19-Aug-2018

Summary

Gene symbol
qars-1
Gene description
Probable glutamine--tRNA ligase
Primary source
WormBase:WBGene00001336
Locus tag
CELE_Y41E3.4
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See qars-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (15008630..15013176, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene human FANCD2 (Fanconi's anemia defect) ortholog Neighboring gene hypothetical protein

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
glutamine-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutamine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
glutaminyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutaminyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of stress-activated MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
 
translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
aminoacyl-tRNA synthetase multienzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Probable glutamine--tRNA ligase
NP_001255843.1
  • Confirmed by transcript evidence
NP_001255844.1
  • Confirmed by transcript evidence
NP_001255845.1
  • Confirmed by transcript evidence
NP_001263821.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    15008630..15013176 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268914.1NP_001255843.1  Probable glutamine--tRNA ligase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255843.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O62431
    Conserved Domains (5) summary
    PLN02859
    Location:1785
    PLN02859; glutamine-tRNA ligase
    cd00807
    Location:269573
    GlnRS_core; catalytic core domain of glutaminyl-tRNA synthetase
    pfam03950
    Location:571761
    tRNA-synt_1c_C; tRNA synthetases class I (E and Q), anti-codon binding domain
    pfam04557
    Location:162262
    tRNA_synt_1c_R2; Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
    pfam04558
    Location:7159
    tRNA_synt_1c_R1; Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1
  2. NM_001268915.1NP_001255844.1  Probable glutamine--tRNA ligase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255844.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3YT95
    Conserved Domains (4) summary
    cd00807
    Location:43347
    GlnRS_core; catalytic core domain of glutaminyl-tRNA synthetase
    PRK05347
    Location:42553
    PRK05347; glutaminyl-tRNA synthetase; Provisional
    pfam03950
    Location:345535
    tRNA-synt_1c_C; tRNA synthetases class I (E and Q), anti-codon binding domain
    pfam04557
    Location:136
    tRNA_synt_1c_R2; Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
  3. NM_001268916.1NP_001255845.1  Probable glutamine--tRNA ligase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255845.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3YT96
    Conserved Domains (2) summary
    pfam03950
    Location:201391
    tRNA-synt_1c_C; tRNA synthetases class I (E and Q), anti-codon binding domain
    cl00015
    Location:58203
    nt_trans; nucleotidyl transferase superfamily
  4. NM_001276892.1NP_001263821.1  Probable glutamine--tRNA ligase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001263821.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    I2HAI0
    Conserved Domains (1) summary
    pfam03950
    Location:1187
    tRNA-synt_1c_C; tRNA synthetases class I (E and Q), anti-codon binding domain
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