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rfc-3 Replication factor C subunit 3 [ Caenorhabditis elegans ]

Gene ID: 178259, updated on 23-Nov-2023

Summary

Gene symbol
rfc-3
Gene description
Replication factor C subunit 3
Primary source
WormBase:WBGene00004339
Locus tag
CELE_C39E9.13
See related
AllianceGenome:WB:WBGene00004339
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA repair and DNA-dependent DNA replication. Predicted to be part of DNA replication factor C complex. Predicted to be active in nucleus. Orthologous to human RFC3 (replication factor C subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See rfc-3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (13095762..13096997)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Proline-rich protein PRCC Neighboring gene SAP domain-containing protein Neighboring gene Dynein light intermediate chain Neighboring gene Putative exosome complex component RRP41 Neighboring gene Mitochondrial import inner membrane translocase subunit Tim10B Neighboring gene RAP domain-containing protein

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to DNA clamp loader activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA-templated DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of DNA replication factor C complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Replication factor C subunit 3
NP_502517.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13095762..13096997
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070116.9NP_502517.1  Replication factor C subunit 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502517.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18547
    Conserved Domains (3) summary
    cd00009
    Location:38187
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    PRK12402
    Location:3342
    PRK12402; replication factor C small subunit 2; Reviewed
    pfam08542
    Location:253340
    Rep_fac_C; Replication factor C C-terminal domain