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let-60 Ras protein let-60 [ Caenorhabditis elegans ]

Gene ID: 178104, updated on 5-Sep-2019

Summary

Gene symbol
let-60
Gene description
Ras protein let-60
Primary source
WormBase:WBGene00002335
Locus tag
CELE_ZK792.6
Gene type
protein coding
RNA name
Ras protein let-60
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See let-60 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (11688227..11691090, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ANK_REP_REGION domain-containing protein Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene hypothetical protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
GDP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Rap guanyl-nucleotide exchange factor activity IDA
Inferred from Direct Assay
more info
PubMed 
NOT Ras guanyl-nucleotide exchange factor activity IDA
Inferred from Direct Assay
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phospholipase binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
associative learning IGI
Inferred from Genetic Interaction
more info
PubMed 
epidermal growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
epidermal growth factor receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
muscle organ development IGI
Inferred from Genetic Interaction
more info
PubMed 
muscle organ development IMP
Inferred from Mutant Phenotype
more info
PubMed 
nematode larval development IGI
Inferred from Genetic Interaction
more info
PubMed 
nematode larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
oogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
NOT positive regulation of GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of receptor localization to synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of vulval development IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of vulval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell projection organization IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of cell projection organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of vulval development IGI
Inferred from Genetic Interaction
more info
PubMed 
reproduction IGI
Inferred from Genetic Interaction
more info
PubMed 
short-term memory IGI
Inferred from Genetic Interaction
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
vulval cell fate specification IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Ras protein let-60
NP_502213.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    11688227..11691090 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069812.4NP_502213.3  Ras protein let-60 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502213.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P22981
    Conserved Domains (2) summary
    cd04138
    Location:3164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    smart00010
    Location:16166
    small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily
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