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dif-1 Protein dif-1 [ Caenorhabditis elegans ]

Gene ID: 177530, updated on 22-May-2024

Summary

Gene symbol
dif-1
Gene description
Protein dif-1
Primary source
WormBase:WBGene00000996
Locus tag
CELE_F49E8.5
See related
AllianceGenome:WB:WBGene00000996
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ATP:ADP antiporter activity. Involved in mitochondrial transport. Located in mitochondrial envelope. Is expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Orthologous to human SLC25A20 (solute carrier family 25 member 20). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See dif-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (7551657..7552874, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Puromycin-sensitive aminopeptidase Neighboring gene Cytidine deaminase Neighboring gene C2H2-type domain-containing protein Neighboring gene Early nodulin-75-like Neighboring gene BACK domain-containing protein Neighboring gene Phosphatidylinositol-glycan biosynthesis class F protein Neighboring gene Nitrogen permease regulator 2

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP:ADP antiporter activity IEA
Inferred from Electronic Annotation
more info
 
enables acyl carnitine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in acyl carnitine transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in carnitine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitochondrial ADP transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial ATP transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitochondrial transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrial envelope IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial envelope IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Protein dif-1
NP_001379917.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7551657..7552874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392331.1NP_001379917.1  Protein dif-1 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q20630, Q27257
    Conserved Domains (1) summary
    pfam00153
    Location:100198
    Mito_carr; Mitochondrial carrier protein