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dpf-5 acylaminoacyl-peptidase [ Caenorhabditis elegans ]

Gene ID: 177251, updated on 6-Jul-2026
Official Symbol
dpf-5
Official Full Name
acylaminoacyl-peptidase
Primary source
WormBase:WBGene00001058
Locus tag
CELE_R11E3.8
See related
AllianceGenome:WB:WBGene00001058
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Is expressed in intestine and rectal gland cell. Orthologous to human APEH (acylaminoacyl-peptide hydrolase). [provided by Alliance of Genome Resources, Jul 2025]
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See dpf-5 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (4802702..4806586, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein;Zinc finger protein Neighboring gene ncRNA Neighboring gene Dipeptidyl Peptidase Four (IV) family Neighboring gene uncharacterized protein Neighboring gene UBX domain-containing protein 6 Neighboring gene uncharacterized protein

Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
  2. MACSPI enables tissue-selective proteomic and interactomic analyses in multicellular organisms. Huang S, et al. Proc Natl Acad Sci U S A, 2024 May 21. PMID 38753516, Free PMC Article
  3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables omega peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
acylaminoacyl-peptidase
NP_001368236.1
  • Confirmed by transcript evidence
NP_500647.2
  • Confirmed by transcript evidence

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    4802702..4806586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068246.7 → NP_500647.2  acylaminoacyl-peptidase

    See identical proteins and their annotated locations for NP_500647.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TYX1
    Conserved Domains (1) summary
    COG1506
    Location:167 → 737
    DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]

  2. NM_001380210.1 → NP_001368236.1  acylaminoacyl-peptidase

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PB38
    Conserved Domains (1) summary
    COG1506
    Location:12 → 582
    DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]
Nucleotide Protein
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Gene LinkOut

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