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dpf-5 acylaminoacyl-peptidase [ Caenorhabditis elegans ]

Gene ID: 177251, updated on 7-Apr-2025

Summary

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Official Symbol
dpf-5
Official Full Name
acylaminoacyl-peptidase
Primary source
WormBase:WBGene00001058
Locus tag
CELE_R11E3.8
See related
AllianceGenome:WB:WBGene00001058
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Is expressed in intestine and rectal gland cell. Orthologous to human APEH (acylaminoacyl-peptide hydrolase). [provided by Alliance of Genome Resources, Apr 2025]
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Genomic context

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See dpf-5 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (4802702..4806586, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein;Zinc finger protein Neighboring gene ncRNA Neighboring gene Dipeptidyl Peptidase Four (IV) family Neighboring gene Uncharacterized protein Neighboring gene UBX domain-containing protein 6 Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
  2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  3. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
acylaminoacyl-peptidase
NP_001368236.1
  • Confirmed by transcript evidence
NP_500647.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    4802702..4806586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068246.7 → NP_500647.2  acylaminoacyl-peptidase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500647.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TYX1
    Conserved Domains (1) summary
    COG1506
    Location:167 → 737
    DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]

  2. NM_001380210.1 → NP_001368236.1  acylaminoacyl-peptidase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PB38
    Conserved Domains (1) summary
    COG1506
    Location:12 → 582
    DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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