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mdf-2 HORMA domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177046, updated on 19-Oct-2019

Summary

Gene symbol
mdf-2
Gene description
HORMA domain-containing protein
Primary source
WormBase:WBGene00003161
Locus tag
CELE_Y69A2AR.30
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See mdf-2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (2636227..2641117, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene NRAMP-like transporter smf-3 Neighboring gene BHLH domain-containing protein Neighboring gene ncRNA Neighboring gene tRNA Neighboring gene hypothetical protein Neighboring gene Synembryn

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the mdf-2 gene: The mdf-2 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic spindle assembly checkpoint IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic spindle assembly checkpoint IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle assembly checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell cycle IGI
Inferred from Genetic Interaction
more info
PubMed 
response to anoxia IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
condensed chromosome kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
condensed nuclear chromosome kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
pronucleus IDA
Inferred from Direct Assay
more info
PubMed 
spindle midzone IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
HORMA domain-containing protein
NP_001023563.1
  • Confirmed by transcript evidence
NP_001294613.1
  • Confirmed by transcript evidence
NP_001360134.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    2636227..2641117 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001028392.6NP_001023563.1  HORMA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023563.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGT3
    Conserved Domains (1) summary
    pfam02301
    Location:12191
    HORMA; HORMA domain
  2. NM_001307684.2NP_001294613.1  HORMA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294613.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PC21
    Conserved Domains (1) summary
    pfam02301
    Location:11128
    HORMA; HORMA domain
  3. NM_001372749.1NP_001360134.1  HORMA domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

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