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rfc-2 AAA+ ATPase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176946, updated on 23-Nov-2023

Summary

Gene symbol
rfc-2
Gene description
AAA+ ATPase domain-containing protein
Primary source
WormBase:WBGene00004338
Locus tag
CELE_F58F6.4
See related
AllianceGenome:WB:WBGene00004338
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA repair and DNA-dependent DNA replication. Predicted to be part of DNA replication factor C complex. Predicted to be active in nucleus. Is expressed in intestine and nervous system. Orthologous to human RFC2 (replication factor C subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See rfc-2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (1347314..1352977)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene tRNA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to DNA clamp loader activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA-templated DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of DNA replication factor C complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
AAA+ ATPase domain-containing protein
NP_500069.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    1347314..1352977
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067668.7NP_500069.1  AAA+ ATPase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500069.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44175
    Conserved Domains (1) summary
    PLN03025
    Location:11325
    PLN03025; replication factor C subunit; Provisional