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prdx-6 PeRoxireDoXin [ Caenorhabditis elegans ]

Gene ID: 176837, updated on 12-Aug-2018

Summary

Gene symbol
prdx-6
Gene description
PeRoxireDoXin
Primary source
WormBase:WBGene00021401
Locus tag
CELE_Y38C1AA.11
Gene type
protein coding
RNA name
PeRoxireDoXin
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See prdx-6 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (218567..220769)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Cytochrome Oxidase Assembly subunits Neighboring gene hypothetical protein Neighboring gene General Transcription Factor homolog Neighboring gene hypothetical protein

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
antioxidant activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
peroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxiredoxin activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cellular oxidant detoxification IEA
Inferred from Electronic Annotation
more info
 
cellular response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrogen peroxide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cell IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
PeRoxireDoXin
NP_741287.1
  • Product from WormBase gene class prdx;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    218567..220769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171241.3NP_741287.1  PeRoxireDoXin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741287.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MXT1
    Conserved Domains (2) summary
    COG0450
    Location:3194
    AhpC; Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin) [Defense mechanisms]
    cd03016
    Location:3221
    PRX_1cys; Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by ...
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