T27E9.2 Cytochrome b-c1 complex subunit 6 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: T27E9.2
Official Full Name: Cytochrome b-c1 complex subunit 6
Primary source: WormBase:WBGene00012094
Locus tag: CELE_T27E9.2
See related: AllianceGenome:WB:WBGene00012094
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Orthologous to human UQCRH (ubiquinol-cytochrome c reductase hinge protein) and UQCRHL (ubiquinol-cytochrome c reductase hinge protein like). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See T27E9.2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 1

Sequence:: Chromosome: III; NC_003281.10 (13462357..13462584, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T27E9.1 (e-PCR)
- UniSTS:311044

Y76A2A.1 (e-PCR)
- UniSTS:312892

T27E9.7 (e-PCR)
- UniSTS:312787

T27E9.2 (e-PCR)
- UniSTS:320757

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex III	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex III	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Cytochrome b-c1 complex subunit 6

NP_499781.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

13462357..13462584 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067380.6 → NP_499781.1 Cytochrome b-c1 complex subunit 6 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499781.1

Status: REVIEWED

UniProtKB/TrEMBL

O45864

Conserved Domains (1) summary

pfam02320
Location:14 → 74

UCR_hinge; Ubiquinol-cytochrome C reductase hinge protein