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chc-1 putative clathrin heavy chain 1 [ Caenorhabditis elegans ]

Gene ID: 176434, updated on 10-Aug-2021

Summary

Gene symbol
chc-1
Gene description
putative clathrin heavy chain 1
Primary source
WormBase:WBGene00011867
Locus tag
CELE_T20G5.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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Genomic context

See chc-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
10
Sequence:
Chromosome: III; NC_003281.10 (10203821..10209704)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene DB domain-containing protein Neighboring gene DB domain-containing protein Neighboring gene ncRNA Neighboring gene Partner of Y14 and mago Neighboring gene Biogenesis of lysosome-related organelles complex 1 subunit 1 Neighboring gene Bestrophin homolog 18 Neighboring gene putative citrate synthase, mitochondrial

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the chc-1 gene: The chc-1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables clathrin light chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables clathrin light chain binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
part_of clathrin coat of coated pit IEA
Inferred from Electronic Annotation
more info
 
part_of clathrin coat of trans-Golgi network vesicle IEA
Inferred from Electronic Annotation
more info
 
part_of clathrin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of clathrin complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in clathrin-coated endocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in clathrin-coated endocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in clathrin-coated pit IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
located_in endocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitotic spindle IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
putative clathrin heavy chain 1
NP_499260.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10203821..10209704
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066859.5NP_499260.1  putative clathrin heavy chain 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499260.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34574
    Conserved Domains (5) summary
    smart00299
    Location:12761418
    CLH; Clathrin heavy chain repeat homology
    pfam00637
    Location:9851121
    Clathrin; Region in Clathrin and VPS
    pfam01394
    Location:196232
    Clathrin_propel; Clathrin propeller repeat
    pfam09268
    Location:329351
    Clathrin-link; Clathrin, heavy-chain linker
    pfam13838
    Location:362419
    Clathrin_H_link; Clathrin-H-link
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