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spop-1 BTB and MATH domain-containing protein 43 [ Caenorhabditis elegans ]

Gene ID: 176422, updated on 17-Nov-2020

Summary

Gene symbol
spop-1
Gene description
BTB and MATH domain-containing protein 43
Primary source
WormBase:WBGene00011815
Locus tag
CELE_T16H12.5
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See spop-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (10090862..10098081, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene General transcription factor IIH subunit 2 Neighboring gene Kelch repeat-containing protein kel-10 Neighboring gene pseudo

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the spop-1 gene: The spop-1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
regulation of proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
BTB and MATH domain-containing protein 43
NP_001022764.1
  • Confirmed by transcript evidence
NP_001022765.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10090862..10098081 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027593.2NP_001022764.1  BTB and MATH domain-containing protein 43 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022764.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34568
    Conserved Domains (4) summary
    smart00225
    Location:266368
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cd03774
    Location:92230
    MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
    cd14734
    Location:368430
    SPOP_C; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins
    pfam00651
    Location:255365
    BTB; BTB/POZ domain
  2. NM_001027594.5NP_001022765.1  BTB and MATH domain-containing protein 43 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022765.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34568
    Conserved Domains (4) summary
    smart00225
    Location:224326
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cd03774
    Location:50188
    MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
    cd14734
    Location:326388
    SPOP_C; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins
    pfam00651
    Location:213323
    BTB; BTB/POZ domain
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