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unc-32 Probable V-type proton ATPase 116 kDa subunit a [ Caenorhabditis elegans ]

Gene ID: 176257, updated on 19-Oct-2019

Summary

Gene symbol
unc-32
Gene description
Probable V-type proton ATPase 116 kDa subunit a
Primary source
WormBase:WBGene00006768
Locus tag
CELE_ZK637.8
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See unc-32 in Genome Data Viewer
Location:
chromosome: III
Exon count:
13
Sequence:
Chromosome: III; NC_003281.10 (8905615..8911752)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein lin-9 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Thiamin pyrophosphokinase 1 Neighboring gene Probable glutathione reductase 2 Neighboring gene M-phase inducer phosphatase cdc-25.3

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the unc-32 gene: The unc-32 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
ATPase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
proton-transporting ATPase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
ATP synthesis coupled proton transport NAS
Non-traceable Author Statement
more info
PubMed 
defense response to Gram-positive bacterium IGI
Inferred from Genetic Interaction
more info
PubMed 
embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
PubMed 
ion transport IEA
Inferred from Electronic Annotation
more info
 
locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of locomotion NAS
Non-traceable Author Statement
more info
PubMed 
nematode larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of programmed cell death IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
response to hypoxia IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic transmission, cholinergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
vacuolar acidification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane NAS
Non-traceable Author Statement
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proton-transporting V-type ATPase, V0 domain IEA
Inferred from Electronic Annotation
more info
 
vacuolar proton-transporting V-type ATPase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vacuolar proton-transporting V-type ATPase complex IPI
Inferred from Physical Interaction
more info
PubMed 
vacuolar proton-transporting V-type ATPase, V0 domain IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Probable V-type proton ATPase 116 kDa subunit a
NP_001023017.1
  • Confirmed by transcript evidence
NP_001023018.1
  • Confirmed by transcript evidence
NP_001023019.1
  • Confirmed by transcript evidence
NP_001023020.1
  • Confirmed by transcript evidence
NP_001023021.1
  • Confirmed by transcript evidence
NP_001023022.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8905615..8911752
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027849.2NP_001023020.1  Probable V-type proton ATPase 116 kDa subunit a [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023020.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P30628
    Conserved Domains (2) summary
    COG1269
    Location:40886
    NtpI; Archaeal/vacuolar-type H+-ATPase subunit I/STV1 [Energy production and conversion]
    pfam01496
    Location:40885
    V_ATPase_I; V-type ATPase 116kDa subunit family
  2. NM_001027847.3NP_001023018.1  Probable V-type proton ATPase 116 kDa subunit a [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023018.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P30628
    Conserved Domains (2) summary
    COG1269
    Location:40870
    NtpI; Archaeal/vacuolar-type H+-ATPase subunit I/STV1 [Energy production and conversion]
    pfam01496
    Location:40869
    V_ATPase_I; V-type ATPase 116kDa subunit family
  3. NM_001027846.2NP_001023017.1  Probable V-type proton ATPase 116 kDa subunit a [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023017.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P30628
    Conserved Domains (2) summary
    COG1269
    Location:40892
    NtpI; Archaeal/vacuolar-type H+-ATPase subunit I/STV1 [Energy production and conversion]
    pfam01496
    Location:40891
    V_ATPase_I; V-type ATPase 116kDa subunit family
  4. NM_001027851.2NP_001023022.1  Probable V-type proton ATPase 116 kDa subunit a [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023022.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P30628
    Conserved Domains (2) summary
    COG1269
    Location:40876
    NtpI; Archaeal/vacuolar-type H+-ATPase subunit I/STV1 [Energy production and conversion]
    pfam01496
    Location:40875
    V_ATPase_I; V-type ATPase 116kDa subunit family
  5. NM_001027850.4NP_001023021.1  Probable V-type proton ATPase 116 kDa subunit a [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023021.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P30628
    Conserved Domains (2) summary
    COG1269
    Location:40875
    NtpI; Archaeal/vacuolar-type H+-ATPase subunit I/STV1 [Energy production and conversion]
    pfam01496
    Location:40874
    V_ATPase_I; V-type ATPase 116kDa subunit family
  6. NM_001027848.5NP_001023019.1  Probable V-type proton ATPase 116 kDa subunit a [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023019.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P30628
    Conserved Domains (2) summary
    COG1269
    Location:40881
    NtpI; Archaeal/vacuolar-type H+-ATPase subunit I/STV1 [Energy production and conversion]
    pfam01496
    Location:40880
    V_ATPase_I; V-type ATPase 116kDa subunit family
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