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ubq-1 Ubiquitin-related [ Caenorhabditis elegans ]

Gene ID: 175840, updated on 23-Nov-2023

Summary

Gene symbol
ubq-1
Gene description
Ubiquitin-related
Primary source
WormBase:WBGene00006727
Locus tag
CELE_F25B5.4
See related
AllianceGenome:WB:WBGene00006727
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tag and ubiquitin protein ligase binding activity. Involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. Is expressed in body wall musculature; hypodermis; and neurons. Orthologous to several human genes including UBC (ubiquitin C). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See ubq-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (5940986..5943827)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Matrix metalloproteinase-A Neighboring gene Ovule protein Neighboring gene Uncharacterized protein Neighboring gene CDK5RAP1-like protein Neighboring gene Putative folylpolyglutamate synthase

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tag activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in modification-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in programmed cell death involved in cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Ubiquitin-related
NP_741157.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5940986..5943827
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171139.8NP_741157.1  Ubiquitin-related [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741157.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P0CG71
    Conserved Domains (2) summary
    cd01803
    Location:77152
    Ubiquitin; Ubiquitin
    smart00213
    Location:172
    UBQ; Ubiquitin homologues