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pxl-1 Paxillin homolog 1 [ Caenorhabditis elegans ]

Gene ID: 175831, updated on 10-Oct-2019

Summary

Gene symbol
pxl-1
Gene description
Paxillin homolog 1
Primary source
WormBase:WBGene00016197
Locus tag
CELE_C28H8.6
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See pxl-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
10
Sequence:
Chromosome: III; NC_003281.10 (5889719..5896017, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ShKT domain-containing protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene Zinc finger protein dpff-1 Neighboring gene ER lumen protein-retaining receptor erd-2.2

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vinculin binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
muscle structure development IMP
Inferred from Mutant Phenotype
more info
PubMed 
nematode larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
pharyngeal pumping IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of nucleic acid-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
M band IDA
Inferred from Direct Assay
more info
PubMed 
M band IEA
Inferred from Electronic Annotation
more info
 
adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
adherens junction IEA
Inferred from Electronic Annotation
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
podosome IDA
Inferred from Direct Assay
more info
PubMed 
podosome IEA
Inferred from Electronic Annotation
more info
 
striated muscle dense body IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Paxillin homolog 1
NP_001021185.2
  • Confirmed by transcript evidence
NP_001021186.1
  • Confirmed by transcript evidence
NP_001122677.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5889719..5896017 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129205.2NP_001122677.1  Paxillin homolog 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122677.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09476
    Conserved Domains (4) summary
    cd09338
    Location:233285
    LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
    cd09339
    Location:292343
    LIM4_Paxillin_like; The fourth LIM domain of the Paxillin-like protein family
    pfam00412
    Location:174229
    LIM; LIM domain
    cl02475
    Location:113167
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  2. NM_001026014.3NP_001021185.2  Paxillin homolog 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021185.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09476
    Conserved Domains (4) summary
    cd09338
    Location:294346
    LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
    cd09339
    Location:353404
    LIM4_Paxillin_like; The fourth LIM domain of the Paxillin-like protein family
    cd09406
    Location:174228
    LIM1_Leupaxin; The first LIM domain of Leupaxin
    pfam00412
    Location:235290
    LIM; LIM domain
  3. NM_001026015.3NP_001021186.1  Paxillin homolog 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021186.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09476
    Conserved Domains (2) summary
    pfam00412
    Location:148203
    LIM; LIM domain
    cl02475
    Location:87141
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
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