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sel-2 Putative neurobeachin homolog [ Caenorhabditis elegans ]

Gene ID: 175606, updated on 5-Sep-2019

Summary

Gene symbol
sel-2
Gene description
Putative neurobeachin homolog
Primary source
WormBase:WBGene00004760
Locus tag
CELE_F10F2.1
Gene type
protein coding
RNA name
Putative neurobeachin homolog
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See sel-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
32
Sequence:
Chromosome: III; NC_003281.10 (4596059..4612384, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Anaphase-promoting complex subunit 11 Neighboring gene ATP Synthase B homolog Neighboring gene Protein male abnormal 21 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
apical protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
endosomal transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of Notch signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of vulval development IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Putative neurobeachin homolog
NP_497939.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4596059..4612384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065538.6NP_497939.2  Putative neurobeachin homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497939.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19317
    Conserved Domains (8) summary
    COG2319
    Location:22332489
    WD40; WD40 repeat [General function prediction only]
    pfam02138
    Location:18312106
    Beach; Beige/BEACH domain
    pfam06469
    Location:15131677
    DUF1088; Domain of Unknown Function (DUF1088)
    pfam14844
    Location:17011798
    PH_BEACH; PH domain associated with Beige/BEACH
    pfam15787
    Location:544820
    DUF4704; Domain of unknown function (DUF4704)
    sd00039
    Location:22272265
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:22352479
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl22861
    Location:328474
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
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