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atf-7 Transcription factor atf-7 [ Caenorhabditis elegans ]

Gene ID: 175587, updated on 23-Nov-2023

Summary

Gene symbol
atf-7
Gene description
Transcription factor atf-7
Primary source
WormBase:WBGene00000223
Locus tag
CELE_C07G2.2
See related
AllianceGenome:WB:WBGene00000223
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and mitogen-activated protein kinase binding activity. Involved in several processes, including defense response to bacterium; regulation of innate immune response; and regulation of transcription by RNA polymerase II. Acts upstream of or within serotonin biosynthetic process. Located in chromatin and nucleus. Is expressed in body wall musculature; hypodermis; intestine; neurons; and rectal epithelial cell. Orthologous to human ATF2 (activating transcription factor 2); ATF7 (activating transcription factor 7); and CREB5 (cAMP responsive element binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (4491627..4499045, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Insulin-like peptide 17 Neighboring gene Chondroitin proteoglycan 1 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene T-complex protein 1 subunit epsilon Neighboring gene Protein kinase domain-containing protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
part_of chromatin IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Transcription factor atf-7
NP_001370161.1
  • Confirmed by transcript evidence
NP_001379489.1
  • Confirmed by transcript evidence
NP_497913.1
  • Confirmed by transcript evidence
NP_497914.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4491627..4499045 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065513.5NP_497914.2  Transcription factor atf-7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497914.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U3R1
    Conserved Domains (2) summary
    smart00338
    Location:340404
    BRLZ; basic region leucin zipper
    cd14687
    Location:345396
    bZIP_ATF2; coiled coil [structural motif]
  2. NM_001393322.1NP_001379489.1  Transcription factor atf-7 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (2) summary
    smart00338
    Location:321372
    BRLZ; basic region leucin zipper
    cd14687
    Location:326372
    bZIP_ATF2; coiled coil [structural motif]
  3. NM_065512.5NP_497913.1  Transcription factor atf-7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497913.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17801
    Conserved Domains (2) summary
    smart00338
    Location:340407
    BRLZ; basic region leucin zipper
    cd14687
    Location:345399
    bZIP_ATF2; coiled coil [structural motif]
  4. NM_001384076.2NP_001370161.1  Transcription factor atf-7 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3GWA6, Q17801, Q86MD3, Q9U3R1
    Conserved Domains (2) summary
    smart00338
    Location:389456
    BRLZ; basic region leucin zipper
    cd14687
    Location:394448
    bZIP_ATF2; coiled coil [structural motif]