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mtm-3 Myotubularin-related protein 3 [ Caenorhabditis elegans ]

Gene ID: 175490, updated on 10-Aug-2021

Summary

Gene symbol
mtm-3
Gene description
Myotubularin-related protein 3
Primary source
WormBase:WBGene00003476
Locus tag
CELE_T24A11.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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Genomic context

See mtm-3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
10
Sequence:
Chromosome: III; NC_003281.10 (3789982..3800467, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Adenylyl CYclase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene X-BoX promoter element regulated Neighboring gene Zinc metalloproteinase nas-26

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables inositol bisphosphate phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol trisphosphate phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables phosphatidylinositol-3-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphatidylinositol-3-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphatidylinositol-3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol-3-phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein phosphatase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in inositol phosphate dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of engulfment of apoptotic cell IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphatidylinositol dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in phosphatidylinositol dephosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of autophagosome maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of autophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of oviposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to starvation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in extrinsic component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Myotubularin-related protein 3
NP_001022794.2
  • Partially confirmed by transcript evidence
NP_497766.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    3789982..3800467 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027623.7NP_001022794.2  Myotubularin-related protein 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022794.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22712
    Conserved Domains (2) summary
    smart00064
    Location:814883
    FYVE; Protein present in Fab1, YOTB, Vac1, and EEA1
    pfam06602
    Location:258574
    Myotub-related; Myotubularin-like phosphatase domain
  2. NM_065365.10NP_497766.3  Myotubularin-related protein 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497766.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22712
    Conserved Domains (2) summary
    smart00064
    Location:810879
    FYVE; Protein present in Fab1, YOTB, Vac1, and EEA1
    pfam06602
    Location:254570
    Myotub-related; Myotubularin-like phosphatase domain
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