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sel-8 Protein lag-3 [ Caenorhabditis elegans ]

Gene ID: 175464, updated on 19-Oct-2019

Summary

Gene symbol
sel-8
Gene description
Protein lag-3
Primary source
WormBase:WBGene00004765
Locus tag
CELE_C32A3.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See sel-8 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (3611925..3627142, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Tyrosine-protein phosphatase 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 28S ribosomal protein S31, mitochondrial Neighboring gene ncRNA

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
transcription coactivator activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
Notch signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
Notch signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of stem cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
RNA polymerase II transcription factor complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Protein lag-3
NP_001021194.1
  • Confirmed by transcript evidence
NP_001021195.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    3611925..3627142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026023.3NP_001021194.1  Protein lag-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021194.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09260
    Conserved Domains (1) summary
    pfam11498
    Location:23490
    Activator_LAG-3; Transcriptional activator LAG-3
  2. NM_001026024.3NP_001021195.1  Protein lag-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021195.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09260
    Conserved Domains (1) summary
    pfam11498
    Location:1468
    Activator_LAG-3; Transcriptional activator LAG-3
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