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Y53G8B.2 Acyltransferase [ Caenorhabditis elegans ]

Gene ID: 175417, updated on 3-May-2025
Official Symbol
Y53G8B.2
Official Full Name
Acyltransferase
Primary source
WormBase:WBGene00021818
Locus tag
CELE_Y53G8B.2
See related
AllianceGenome:WB:WBGene00021818
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatotic liver disease. Orthologous to several human genes including MOGAT1 (monoacylglycerol O-acyltransferase 1) and MOGAT2 (monoacylglycerol O-acyltransferase 2). [provided by Alliance of Genome Resources, May 2025]
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Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (3101229..3103955, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tRNA Neighboring gene tRNA Neighboring gene tRNA Neighboring gene tRNA Neighboring gene tRNA

Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables diacylglycerol O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in triglyceride biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
Acyltransferase
NP_497659.1
  • Confirmed by transcript evidence

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    3101229..3103955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065258.6 → NP_497659.1  Acyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497659.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N4S3
    Conserved Domains (1) summary
    pfam03982
    Location:44 → 340
    DAGAT; Diacylglycerol acyltransferase
Nucleotide Protein
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