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zer-1 Zyg eleven-related protein 1 [ Caenorhabditis elegans ]

Gene ID: 175249, updated on 4-Jan-2025

Summary

Official Symbol
zer-1
Official Full Name
Zyg eleven-related protein 1
Primary source
WormBase:WBGene00020762
Locus tag
CELE_T24C4.6
See related
AllianceGenome:WB:WBGene00020762
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Part of Cul2-RING ubiquitin ligase complex. Orthologous to human ZER1 (zyg-11 related cell cycle regulator). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See zer-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (881443..886789, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene DUF2975 domain-containing protein Neighboring gene Transmembrane protein 225 Neighboring gene DNA primase Neighboring gene Peptidase M16 N-terminal domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene C2H2-type domain-containing protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of Cul2-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Cul2-RING ubiquitin ligase complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of Cul2-RING ubiquitin ligase complex IPI
Inferred from Physical Interaction
more info
PubMed 
part_of Cul2-RING ubiquitin ligase complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
Zyg eleven-related protein 1
NP_741089.2
  • Confirmed by transcript evidence
NP_741090.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    881443..886789 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171078.7NP_741089.2  Zyg eleven-related protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741089.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q2WF58, Q2WF59
    Conserved Domains (1) summary
    sd00034
    Location:98123
    LRR_AMN1; leucine-rich repeat [structural motif]
  2. NM_171079.10NP_741090.3  Zyg eleven-related protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741090.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q2WF59
    Conserved Domains (2) summary
    cd00020
    Location:594720
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    sd00034
    Location:98123
    LRR_AMN1; leucine-rich repeat [structural motif]