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imb-2 Importin N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175094, updated on 22-Aug-2021

Summary

Gene symbol
imb-2
Gene description
Importin N-terminal domain-containing protein
Primary source
WormBase:WBGene00002076
Locus tag
CELE_R06A4.4
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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Genomic context

See imb-2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (14365701..14373901)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene pre-mRNA 3' end processing protein pfs-2 Neighboring gene TElomere Binding Protein Neighboring gene AcetylCholine Receptor Neighboring gene SKN-1 Dependent Zygotic transcript Neighboring gene Histone-lysine N-methyltransferase mes-2

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the imb-2 gene: The imb-2 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables nuclear import signal receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nuclear localization sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein import into nucleus IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Importin N-terminal domain-containing protein
NP_001309574.1
  • Confirmed by transcript evidence
NP_496987.1
  • Confirmed by transcript evidence
NP_496988.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14365701..14373901
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001322761.3NP_001309574.1  Importin N-terminal domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBF9
    Conserved Domains (2) summary
    COG5215
    Location:15764
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:388416
    HEAT; HEAT repeat [structural motif]
  2. NM_064587.5NP_496988.1  Importin N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496988.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62333
  3. NM_064586.4NP_496987.1  Importin N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496987.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62332
    Conserved Domains (2) summary
    COG5215
    Location:15758
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:388416
    HEAT; HEAT repeat [structural motif]
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