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lin-7 Protein lin-7 homolog [ Caenorhabditis elegans ]

Gene ID: 175089, updated on 5-Sep-2019

Summary

Gene symbol
lin-7
Gene description
Protein lin-7 homolog
Primary source
WormBase:WBGene00002996
Locus tag
CELE_Y54G11A.10
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See lin-7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (14345842..14348792, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Daf-16-Dependent Longevity (WT but not daf-16 lifespan increased) Neighboring gene Fe-S_biosyn domain-containing protein Neighboring gene hypothetical protein Neighboring gene Transcription elongation factor 1 homolog Neighboring gene AGL (Amylo-1,6-GLucosidase, 4-alpha-glucanotransferase) glycogen debranching enzyme

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
L27 domain binding IEA
Inferred from Electronic Annotation
more info
 
protein C-terminus binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding, bridging IPI
Inferred from Physical Interaction
more info
PubMed 
signaling receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
epidermal growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
exocytosis IEA
Inferred from Electronic Annotation
more info
 
maintenance of epithelial cell apical/basal polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neurotransmitter secretion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neurotransmitter secretion IEA
Inferred from Electronic Annotation
more info
 
oviposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of vulval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
post-embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization to basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein localization to basolateral plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
MPP7-DLG1-LIN7 complex IEA
Inferred from Electronic Annotation
more info
 
basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell-cell junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
presynapse IEA
Inferred from Electronic Annotation
more info
 
synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Protein lin-7 homolog
NP_001122664.2
  • Confirmed by transcript evidence
NP_496982.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14345842..14348792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064581.3NP_496982.2  Protein lin-7 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496982.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U245
    Conserved Domains (2) summary
    cd00992
    Location:90170
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02828
    Location:1361
    L27; L27 domain
  2. NM_001129192.3NP_001122664.2  Protein lin-7 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122664.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A5PEX5
    Conserved Domains (2) summary
    cd00992
    Location:90171
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02828
    Location:1361
    L27; L27 domain
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