U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

acl-7 Phospholipid/glycerol acyltransferase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174916, updated on 12-Jun-2024

Summary

Gene symbol
acl-7
Gene description
Phospholipid/glycerol acyltransferase domain-containing protein
Locus tag
CELE_Y46G5A.21
See related
AllianceGenome:WB:WBGene00012911
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glycerone-phosphate O-acyltransferase activity. Predicted to be involved in ether lipid biosynthetic process; fatty acid metabolic process; and phospholipid biosynthetic process. Predicted to be active in mitochondrial membrane and peroxisomal membrane. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata type 2. Orthologous to human GNPAT (glyceronephosphate O-acyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See acl-7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
10
Sequence:
Chromosome: II; NC_003280.10 (12811888..12816462, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene PABS domain-containing protein Neighboring gene Nuclear receptor domain-containing protein Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene FIP (Fungus-Induced Protein) Related

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycerol-3-phosphate O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glycerone-phosphate O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in ether lipid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phospholipid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in triglyceride biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrial membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in peroxisomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Phospholipid/glycerol acyltransferase domain-containing protein
NP_496725.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    12811888..12816462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064324.9NP_496725.2  Phospholipid/glycerol acyltransferase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496725.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EFP8
    Conserved Domains (2) summary
    cd07993
    Location:120325
    LPLAT_DHAPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like
    COG2937
    Location:47660
    PlsB; Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]