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gpb-1 Guanine nucleotide-binding protein subunit beta-1;WD_REPEATS_REGION domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174803, updated on 5-Sep-2019

Summary

Gene symbol
gpb-1
Gene description
Guanine nucleotide-binding protein subunit beta-1;WD_REPEATS_REGION domain-containing protein
Primary source
WormBase:WBGene00001679
Locus tag
CELE_F13D12.7
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See gpb-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
11
Sequence:
Chromosome: II; NC_003280.10 (11742811..11748603, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Aldedh domain-containing protein;Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial Neighboring gene hypothetical protein Neighboring gene Serine carboxypeptidase ctsa-1.2 Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene ncRNA

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the gpb-1 gene: The gpb-1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of mitotic spindle orientation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of oviposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
heterotrimeric G-protein complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
Guanine nucleotide-binding protein subunit beta-1;WD_REPEATS_REGION domain-containing protein
NP_001254312.1
  • Confirmed by transcript evidence
NP_001254313.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11742811..11748603 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001267383.2NP_001254312.1  Guanine nucleotide-binding protein subunit beta-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254312.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P17343
    Conserved Domains (2) summary
    cd00200
    Location:48340
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:5895
    7WD40; WD40 repeat [structural motif]
  2. NM_001267384.2NP_001254313.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254313.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D1MN68
    Conserved Domains (3) summary
    COG2319
    Location:2153
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:1153
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:136
    7WD40; WD40 repeat [structural motif]
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