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unc-53 Adapter protein unc-53;Calponin-homology (CH) domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174693, updated on 19-Oct-2019

Summary

Gene symbol
unc-53
Gene description
Adapter protein unc-53;Calponin-homology (CH) domain-containing protein
Primary source
WormBase:WBGene00006788
Locus tag
CELE_F45E10.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See unc-53 in Genome Data Viewer
Location:
chromosome: II
Exon count:
24
Sequence:
Chromosome: II; NC_003280.10 (11058047..11089456, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Neighboring gene PPM-type phosphatase domain-containing protein Neighboring gene MFS domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ribosomal Protein, Large subunit

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
actin filament binding TAS
Traceable Author Statement
more info
PubMed 
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
actin cytoskeleton organization ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
backward locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell projection morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
determination of muscle attachment site IMP
Inferred from Mutant Phenotype
more info
PubMed 
mating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
mesodermal cell migration IGI
Inferred from Genetic Interaction
more info
PubMed 
motor neuron axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neurogenesis IEA
Inferred from Electronic Annotation
more info
 
oviposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of axon extension IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of axon extension involved in axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of axon extension involved in axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell migration IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Adapter protein unc-53;Calponin-homology (CH) domain-containing protein
NP_001022169.1
  • Confirmed by transcript evidence
NP_001022170.1
  • Confirmed by transcript evidence
NP_001022171.1
  • Confirmed by transcript evidence
NP_001022172.1
  • Confirmed by transcript evidence
NP_001254271.1
  • Confirmed by transcript evidence
NP_001254272.1
  • Confirmed by transcript evidence
NP_001254273.1
  • Confirmed by transcript evidence
NP_741045.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11058047..11089456 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171039.3NP_741045.1  Adapter protein unc-53 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741045.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7YSI9
    Conserved Domains (4) summary
    smart00382
    Location:12941400
    AAA; ATPases associated with a variety of cellular activities
    pfam00307
    Location:11110
    CH; Calponin homology (CH) domain
    cl11433
    Location:10771134
    DivIC; Septum formation initiator
    cl21455
    Location:12961400
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. NM_001267342.2NP_001254271.1  Calponin-homology (CH) domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254271.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EEU6
    Conserved Domains (4) summary
    smart00382
    Location:12531359
    AAA; ATPases associated with a variety of cellular activities
    pfam00307
    Location:11110
    CH; Calponin homology (CH) domain
    cl11433
    Location:10361093
    DivIC; Septum formation initiator
    cl21455
    Location:12551359
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. NM_001026998.4NP_001022169.1  Adapter protein unc-53 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022169.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7YSI9
    Conserved Domains (4) summary
    smart00382
    Location:12601366
    AAA; ATPases associated with a variety of cellular activities
    pfam00307
    Location:11110
    CH; Calponin homology (CH) domain
    cl11433
    Location:10431100
    DivIC; Septum formation initiator
    cl21455
    Location:12621366
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. NM_001267343.2NP_001254272.1  Calponin-homology (CH) domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254272.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBX1
    Conserved Domains (5) summary
    smart00382
    Location:13241430
    AAA; ATPases associated with a variety of cellular activities
    pfam00307
    Location:11110
    CH; Calponin homology (CH) domain
    pfam15720
    Location:737853
    DUF4675; Domain of unknown function (DUF4675)
    cl11433
    Location:11071164
    DivIC; Septum formation initiator
    cl21455
    Location:13261430
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  5. NM_001026999.6NP_001022170.1  Adapter protein unc-53 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022170.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7YSI9
    Conserved Domains (4) summary
    smart00382
    Location:13651471
    AAA; ATPases associated with a variety of cellular activities
    pfam00307
    Location:11110
    CH; Calponin homology (CH) domain
    cl11433
    Location:11481205
    DivIC; Septum formation initiator
    cl21455
    Location:13671471
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  6. NM_001027000.4NP_001022171.1  Adapter protein unc-53 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022171.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7YSI9
    Conserved Domains (3) summary
    smart00382
    Location:12311337
    AAA; ATPases associated with a variety of cellular activities
    cl11433
    Location:10141071
    DivIC; Septum formation initiator
    cl21455
    Location:12331337
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  7. NM_001267344.2NP_001254273.1  Adapter protein unc-53 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254273.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C8JQR2
    Conserved Domains (3) summary
    smart00382
    Location:10571163
    AAA; ATPases associated with a variety of cellular activities
    cl11433
    Location:840897
    DivIC; Septum formation initiator
    cl21455
    Location:10591163
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  8. NM_001027001.4NP_001022172.1  Adapter protein unc-53 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022172.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7YSI9
    Conserved Domains (4) summary
    smart00382
    Location:9451051
    AAA; ATPases associated with a variety of cellular activities
    pfam05823
    Location:536600
    Gp-FAR-1; Nematode fatty acid retinoid binding protein (Gp-FAR-1)
    cl11433
    Location:728785
    DivIC; Septum formation initiator
    cl21455
    Location:9471051
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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