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cdc-48.1 Transitional endoplasmic reticulum ATPase homolog 1 [ Caenorhabditis elegans ]

Gene ID: 174624, updated on 10-Apr-2019

Summary

Gene symbol
cdc-48.1
Gene description
Transitional endoplasmic reticulum ATPase homolog 1
Primary source
WormBase:WBGene00007352
Locus tag
CELE_C06A1.1
Gene type
protein coding
RNA name
Transitional endoplasmic reticulum ATPase homolog 1
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See cdc-48.1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (10560333..10563390, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the cdc-48.1 gene: The cdc-48.1 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-containing complex binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
ER-associated misfolded protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ER-associated misfolded protein catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
autophagosome maturation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryo development ending in birth or egg hatching IGI
Inferred from Genetic Interaction
more info
PubMed 
macroautophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic spindle disassembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of mitotic cell cycle, embryonic IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein localization to chromatin IGI
Inferred from Genetic Interaction
more info
PubMed 
retrograde protein transport, ER to cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ubiquitin-dependent ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
VCP-NPL4-UFD1 AAA ATPase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
VCP-NPL4-UFD1 AAA ATPase complex IDA
Inferred from Direct Assay
more info
PubMed 
VCP-NPL4-UFD1 AAA ATPase complex IPI
Inferred from Physical Interaction
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Transitional endoplasmic reticulum ATPase homolog 1
NP_496273.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10560333..10563390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063872.4NP_496273.1  Transitional endoplasmic reticulum ATPase homolog 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496273.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P54811
    Conserved Domains (5) summary
    smart01072
    Location:137197
    CDC48_2; Cell division protein 48 (CDC48) domain 2
    TIGR01243
    Location:52775
    CDC48; AAA family ATPase, CDC48 subfamily
    pfam00004
    Location:247376
    AAA; ATPase family associated with various cellular activities (AAA)
    pfam02359
    Location:31112
    CDC48_N; Cell division protein 48 (CDC48), N-terminal domain
    pfam09336
    Location:727771
    Vps4_C; Vps4 C terminal oligomerization domain
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