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eif-3.F Eukaryotic translation initiation factor 3 subunit F [ Caenorhabditis elegans ]

Gene ID: 174478, updated on 18-Sep-2024

Summary

Official Symbol
eif-3.F
Official Full Name
Eukaryotic translation initiation factor 3 subunit F
Primary source
WormBase:WBGene00001229
Locus tag
CELE_D2013.7
See related
AllianceGenome:WB:WBGene00001229
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Involved in translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human EIF3F (eukaryotic translation initiation factor 3 subunit F). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See eif-3.F in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (9331643..9333970)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Dynamin-like GTPase OPA1, mitochondrial Neighboring gene GRAM domain-containing protein Neighboring gene ncRNA Neighboring gene Sterol regulatory element-binding protein cleavage-activating protein;WD_REPEATS_REGION domain-containing protein Neighboring gene Tubulin--tyrosine ligase-like protein 12

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 
enables translation initiation factor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translational initiation IEA
Inferred from Electronic Annotation
more info
 
involved_in formation of cytoplasmic translation initiation complex IEA
Inferred from Electronic Annotation
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic 43S preinitiation complex IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic 48S preinitiation complex IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic translation initiation factor 3 complex IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic translation initiation factor 3 complex, eIF3m IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Eukaryotic translation initiation factor 3 subunit F
NP_495988.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9331643..9333970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063587.7NP_495988.1  Eukaryotic translation initiation factor 3 subunit F [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495988.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18967
    Conserved Domains (1) summary
    cd08064
    Location:7291
    MPN_eIF3f; Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in eIF3f