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cdc-42 Cell division control protein 42 homolog [ Caenorhabditis elegans ]

Gene ID: 174233, updated on 4-Aug-2019

Summary

Gene symbol
cdc-42
Gene description
Cell division control protein 42 homolog
Primary source
WormBase:WBGene00000390
Locus tag
CELE_R07G3.1
Gene type
protein coding
RNA name
Cell division control protein 42 homolog
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See cdc-42 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (7616457..7617480)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Immunoglobulin domain-containing protein oig-4 Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the cdc-42 gene: The cdc-42 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, rice, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
Cdc42 protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Rho protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
cell projection assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
epithelial tube morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of mitotic spindle localization IGI
Inferred from Genetic Interaction
more info
PubMed 
establishment of mitotic spindle orientation IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment or maintenance of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
establishment or maintenance of cell polarity IGI
Inferred from Genetic Interaction
more info
PubMed 
establishment or maintenance of cell polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of clathrin-dependent endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of Golgi organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of actin filament-based process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell shape IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
cell projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
endosome IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
recycling endosome IDA
Inferred from Direct Assay
more info
PubMed 
recycling endosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Cell division control protein 42 homolog
NP_495598.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    7616457..7617480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063197.7NP_495598.1  Cell division control protein 42 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495598.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q05062
    Conserved Domains (2) summary
    smart00174
    Location:6179
    RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
    cd01874
    Location:3177
    Cdc42; cell division cycle 42 (Cdc42) is a small GTPase of the Rho family
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