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Mlf1 myeloid leukemia factor 1 [ Mus musculus (house mouse) ]

Gene ID: 17349, updated on 12-Aug-2019

Summary

Official Symbol
Mlf1provided by MGI
Official Full Name
myeloid leukemia factor 1provided by MGI
Primary source
MGI:MGI:1341819
See related
Ensembl:ENSMUSG00000048416
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HLS7
Expression
Biased expression in testis adult (RPKM 137.0) and heart adult (RPKM 22.3) See more
Orthologs

Genomic context

See Mlf1 in Genome Data Viewer
Location:
3 E1; 3 30.91 cM
Exon count:
8
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (67374097..67400000)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (67178019..67203922)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene short stature homeobox 2 Neighboring gene arginine/serine-rich coiled-coil 1 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC115489690 Neighboring gene G elongation factor, mitochondrial 1 Neighboring gene latexin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell cycle arrest ISO
Inferred from Sequence Orthology
more info
 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
myeloid progenitor cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cell projection IEA
Inferred from Electronic Annotation
more info
 
ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
ciliary base EXP
Inferred from Experiment
more info
PubMed 
cilium IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
motile cilium IDA
Inferred from Direct Assay
more info
PubMed 
non-motile cilium IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
myeloid leukemia factor 1
Names
hematopoietic lineage switch 7
myelodysplasia-myeloid leukemia factor 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039543.2NP_001034632.1  myeloid leukemia factor 1 isoform a

    See identical proteins and their annotated locations for NP_001034632.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK133448, BC027526
    Consensus CDS
    CCDS17395.1
    UniProtKB/TrEMBL
    Q3V042, Q8JZS2
    Related
    ENSMUSP00000058596.8, ENSMUST00000061322.9
    Conserved Domains (1) summary
    pfam10248
    Location:27217
    Mlf1IP; Myelodysplasia-myeloid leukemia factor 1-interacting protein
  2. NM_010801.3NP_034931.2  myeloid leukemia factor 1 isoform b

    See identical proteins and their annotated locations for NP_034931.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region, compared to variant 1. This results in a shorter protein (isoform b) compared to isoform a.
    Source sequence(s)
    AK133448, BC027526
    Consensus CDS
    CCDS17396.1
    UniProtKB/Swiss-Prot
    Q9QWV4
    UniProtKB/TrEMBL
    Q3V042, Q8JZS2
    Related
    ENSMUSP00000077072.5, ENSMUST00000077916.11
    Conserved Domains (1) summary
    pfam10248
    Location:27202
    Mlf1IP; Myelodysplasia-myeloid leukemia factor 1-interacting protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p6 C57BL/6J

    Range
    67374097..67400000
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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