aex-5 Endoprotease aex-5 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: aex-5
Official Full Name: Endoprotease aex-5
Primary source: WormBase:WBGene00000088
Locus tag: CELE_F32A7.6
See related: AllianceGenome:WB:WBGene00000088
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables serine-type endopeptidase activity. Involved in several processes, including neuropeptide processing; positive regulation of digestive system process; and positive regulation of synaptic assembly at neuromuscular junction. Located in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]
NEW: Try the new Gene table
Try the new Transcript table

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables serine-type peptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in defecation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in lipid transport involved in lipid storage	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in locomotion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuropeptide processing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of defecation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of defecation rhythm	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of intestinal lipid absorption	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of locomotion	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of synaptic assembly at neuromuscular junction	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of triglyceride transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein localization to synapse	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteolysis	IEA Inferred from Electronic Annotation more info
involved_in regulation of defecation	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IDA Inferred from Direct Assay more info	PubMed
is_active_in trans-Golgi network	IBA Inferred from Biological aspect of Ancestor more info

NP_493594.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain