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sig-7 Peptidyl-prolyl cis-trans isomerase sig-7 [ Caenorhabditis elegans ]

Gene ID: 172664, updated on 10-Aug-2021

Summary

Gene symbol
sig-7
Gene description
Peptidyl-prolyl cis-trans isomerase sig-7
Primary source
WormBase:WBGene00000890
Locus tag
CELE_F39H2.2
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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Genomic context

See sig-7 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (8646451..8651671)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene GCFC domain-containing protein Neighboring gene t-SNARE coiled-coil homology domain-containing protein Neighboring gene SPSAKWMRF-amide 3 Neighboring gene MoRTal germline Neighboring gene Uncharacterized protein

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the sig-7 gene: The sig-7 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II complex binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables RNA polymerase II complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in nematode larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of DNA-templated transcription, elongation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of RNA splicing IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of developmental growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of gastrulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of histone H3-K36 trimethylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of histone H3-K4 trimethylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of histone H3-K79 dimethylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of mRNA processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of oocyte development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of vulval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein peptidyl-prolyl isomerization IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of phosphorylation of RNA polymerase II C-terminal domain IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in transcriptionally active chromatin IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Peptidyl-prolyl cis-trans isomerase sig-7
NP_001359651.1
  • Confirmed by transcript evidence
NP_492343.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    8646451..8651671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059942.9NP_492343.2  Peptidyl-prolyl cis-trans isomerase sig-7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492343.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EEW6
    Conserved Domains (3) summary
    COG0724
    Location:128346
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd01921
    Location:4169
    cyclophilin_RRM; cyclophilin_RRM: cyclophilin-type peptidylprolyl cis- trans isomerase domain occuring with a C-terminal RNA recognition motif domain (RRM). This subfamily of the cyclophilin domain family contains a number of eukaryotic cyclophilins having the RRM domain ...
    cd12235
    Location:238320
    RRM_PPIL4; RNA recognition motif in peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) and similar proteins
  2. NM_001373191.3NP_001359651.1  Peptidyl-prolyl cis-trans isomerase sig-7 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (2) summary
    cd12235
    Location:169251
    RRM_PPIL4; RNA recognition motif in peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) and similar proteins
    cl00197
    Location:1100
    cyclophilin; cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the immunosuppressive drug ...
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