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mei-1 Meiotic spindle formation protein mei-1 [ Caenorhabditis elegans ]

Gene ID: 172612, updated on 22-Aug-2021

Summary

Gene symbol
mei-1
Gene description
Meiotic spindle formation protein mei-1
Primary source
WormBase:WBGene00003183
Locus tag
CELE_T01G9.5
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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Genomic context

See mei-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (8294874..8296940)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Casein kinase II subunit beta Neighboring gene Nuclear pore complex protein Nup85 Neighboring gene Anion exchange protein Neighboring gene ncRNA Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables MATH domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule-severing ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables microtubule-severing ATPase activity IEA
Inferred from Electronic Annotation
more info
 
enables microtubule-severing ATPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein phosphatase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in embryo development ending in birth or egg hatching IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in female meiotic nuclear division IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in meiotic spindle disassembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in meiotic spindle organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in microtubule depolymerization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in microtubule severing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in microtubule severing IEA
Inferred from Electronic Annotation
more info
 
involved_in microtubule severing IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of meiotic spindle elongation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in striated muscle myosin thick filament assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromatin IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
part_of katanin complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in meiotic spindle IDA
Inferred from Direct Assay
more info
PubMed 
located_in meiotic spindle pole IDA
Inferred from Direct Assay
more info
PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in spindle IDA
Inferred from Direct Assay
more info
PubMed 
located_in spindle IEA
Inferred from Electronic Annotation
more info
 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Meiotic spindle formation protein mei-1
NP_001370150.1
  • Confirmed by transcript evidence
NP_492257.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    8294874..8296940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383460.2NP_001370150.1  Meiotic spindle formation protein mei-1 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (2) summary
    pfam17862
    Location:383423
    AAA_lid_3; AAA+ lid domain
    cd19509
    Location:195359
    RecA-like_VPS4-like; ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains
  2. NM_059856.8NP_492257.1  Meiotic spindle formation protein mei-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492257.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34808
    Conserved Domains (2) summary
    smart00382
    Location:225363
    AAA; ATPases associated with a variety of cellular activities
    pfam00004
    Location:229361
    AAA; ATPase family associated with various cellular activities (AAA)
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