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che-3 Cytoplasmic dynein 2 heavy chain 1 [ Caenorhabditis elegans ]

Gene ID: 172593, updated on 22-May-2018

Summary

Gene symbol
che-3
Gene description
Cytoplasmic dynein 2 heavy chain 1
Primary source
WormBase:WBGene00000485
Locus tag
CELE_F18C12.1
Gene type
protein coding
RNA name
Cytoplasmic dynein 2 heavy chain 1
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See che-3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
48
Sequence:
Chromosome: I; NC_003279.8 (8062059..8081671, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene Receptor Mediated Endocytosis Neighboring gene hypothetical protein

Bibliography

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP-dependent microtubule motor activity, minus-end-directed IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATPase activity IEA
Inferred from Electronic Annotation
more info
 
dynein intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dynein light chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dynein light intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dynein light intermediate chain binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 
microtubule motor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
motor activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell projection organization IEA
Inferred from Electronic Annotation
more info
 
chemosensory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
dauer entry IGI
Inferred from Genetic Interaction
more info
PubMed 
intraciliary retrograde transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transforming growth factor beta receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
non-motile cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of dauer larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
axoneme IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell projection IEA
Inferred from Electronic Annotation
more info
 
ciliary membrane IEA
Inferred from Electronic Annotation
more info
 
cilium IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic dynein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
dynein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dynein complex IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
motile cilium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
non-motile cilium IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Cytoplasmic dynein 2 heavy chain 1
NP_492221.2
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    8062059..8081671 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059820.2NP_492221.2  Cytoplasmic dynein 2 heavy chain 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492221.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19542
    Conserved Domains (6) summary
    pfam03028
    Location:35024161
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08385
    Location:234634
    DHC_N1; Dynein heavy chain, N-terminal region 1
    pfam08393
    Location:10861480
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:27903124
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:31483361
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:15991829
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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