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goa-1 Guanine nucleotide-binding protein G(o) subunit alpha [ Caenorhabditis elegans ]

Gene ID: 172505, updated on 5-Sep-2019

Summary

Gene symbol
goa-1
Gene description
Guanine nucleotide-binding protein G(o) subunit alpha
Primary source
WormBase:WBGene00001648
Locus tag
CELE_C26C6.2
Gene type
protein coding
RNA name
Guanine nucleotide-binding protein G(o) subunit alpha
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See goa-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (7522116..7526716)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Zinc metalloproteinase nas-36 Neighboring gene hypothetical protein Neighboring gene Deacetylase Complex Protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
G protein-coupled acetylcholine receptor activity IGI
Inferred from Genetic Interaction
more info
PubMed 
G protein-coupled acetylcholine receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
G protein-coupled receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G-protein beta/gamma-subunit complex binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G-protein beta/gamma-subunit complex binding IEA
Inferred from Electronic Annotation
more info
 
GTP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
guanyl nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein membrane anchor IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled acetylcholine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
G protein-coupled receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
G protein-coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
adenylate cyclase-modulating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
chemotaxis IEA
Inferred from Electronic Annotation
more info
 
defense response to Gram-negative bacterium IGI
Inferred from Genetic Interaction
more info
PubMed 
dopamine receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of axon regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of synaptic transmission, cholinergic IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of synaptic transmission, cholinergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of feeding behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of oviposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of pharyngeal pumping IGI
Inferred from Genetic Interaction
more info
PubMed 
response to drug IGI
Inferred from Genetic Interaction
more info
PubMed 
response to drug IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to food IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Guanine nucleotide-binding protein G(o) subunit alpha
NP_492108.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7522116..7526716
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059707.6NP_492108.1  Guanine nucleotide-binding protein G(o) subunit alpha [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492108.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P51875
    Conserved Domains (2) summary
    cd00066
    Location:34348
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
    smart00275
    Location:14352
    G_alpha; G protein alpha subunit
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