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FHVs1gp2 protein B2 [ Flock House virus ]

Gene ID: 1724847, updated on 6-May-2024
Gene symbol
FHVs1gp2
Gene description
protein B2
Locus tag
FHVs1gp2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Flock House virus
Lineage
Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Magsaviricetes; Nodamuvirales; Nodaviridae; Alphanodavirus
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Location:
segment: RNA 1
Sequence:
NC_004146.1 (2738..3058)

NC_004146.1Genomic Context describing neighboring genes Neighboring gene protein A;protein B1

Genomic Sequence:
NC_004146.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cytoplasmic granule formation and translational inhibition of nodaviral RNAs in the absence of the double-stranded RNA binding protein B2. Petrillo JE, et al. J Virol, 2013 Dec. PMID 24089564, Free PMC Article
  2. Molecular dissection of Flock house virus protein B2 reveals that electrostatic interactions between N-terminal domains of B2 monomers are critical for dimerization. Seo JK, et al. Virology, 2012 Oct 25. PMID 22721960
  3. The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition. Lingel A, et al. EMBO Rep, 2005 Dec. PMID 16270100, Free PMC Article
  4. Dual modes of RNA-silencing suppression by Flock House virus protein B2. Chao JA, et al. Nat Struct Mol Biol, 2005 Nov. PMID 16228003
  5. Multifunctional Protein A Is the Only Viral Protein Required for Nodavirus RNA Replication Crown Formation. den Boon JA, et al. Viruses, 2022 Dec 3. PMID 36560715, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. B2 binding to double-stranded regions of RNA2 prevents recruitment of RNA2 into cellular structures.
    Title: Cytoplasmic granule formation and translational inhibition of nodaviral RNAs in the absence of the double-stranded RNA binding protein B2.
  2. Our data provide evidence that both monomeric and dimeric B2 proteins function in different modes to suppress RNA silencing.
    Title: Molecular dissection of Flock house virus protein B2 reveals that electrostatic interactions between N-terminal domains of B2 monomers are critical for dimerization.
  3. These results reveal a novel interaction between Flock house virus B2 protein and Dicer that leads to suppression of siRNA biogenesis.
    Title: Suppression of RNA silencing by Flock house virus B2 protein is mediated through its interaction with the PAZ domain of Dicer.
Submit: New GeneRIF Correction

Homology

Preferred Names
protein B2

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004146.1 Reference assembly

    Range
    2738..3058
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_689446.1 protein B2 [Flock House virus]

    See identical proteins and their annotated locations for NP_689446.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P68831
    UniProtKB/TrEMBL
    D0U499, G4WWB1
    Conserved Domains (1) summary
    pfam11473
    Location:1 → 72
    B2; RNA binding protein B2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P68831.1

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