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rpb-5 DNA-directed RNA polymerases I, II, and III subunit RPABC1 [ Caenorhabditis elegans ]

Gene ID: 172412, updated on 2-Nov-2024

Summary

Official Symbol
rpb-5
Official Full Name
DNA-directed RNA polymerases I, II, and III subunit RPABC1
Primary source
WormBase:WBGene00019246
Locus tag
CELE_H27M09.2
See related
AllianceGenome:WB:WBGene00019246
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase II; and transcription elongation by RNA polymerase I. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2E (RNA polymerase II, I and III subunit E). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See rpb-5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003279.8 (6850409..6851253)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Synaptonemal complex protein 4 Neighboring gene RNA helicase Neighboring gene ATP-dependent RNA helicase glh-1

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase I activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to RNA polymerase II activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to RNA polymerase III activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transcription elongation by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
 
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RNA polymerase II, core complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RNA polymerase II, holoenzyme IEA
Inferred from Electronic Annotation
more info
 
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA-directed RNA polymerases I, II, and III subunit RPABC1
NP_491961.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6850409..6851253
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059560.5NP_491961.1  DNA-directed RNA polymerases I, II, and III subunit RPABC1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491961.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9N5K2
    Conserved Domains (3) summary
    PLN03111
    Location:1211
    PLN03111; DNA-directed RNA polymerase II subunit family protein; Provisional
    pfam01191
    Location:139210
    RNA_pol_Rpb5_C; RNA polymerase Rpb5, C-terminal domain
    pfam03871
    Location:593
    RNA_pol_Rpb5_N; RNA polymerase Rpb5, N-terminal domain