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unc-11 Phosphatidylinositol-binding clathrin assembly protein unc-11 [ Caenorhabditis elegans ]

Gene ID: 171952, updated on 5-Sep-2019

Summary

Gene symbol
unc-11
Gene description
Phosphatidylinositol-binding clathrin assembly protein unc-11
Primary source
WormBase:WBGene00006751
Locus tag
CELE_C32E8.10
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See unc-11 in Genome Data Viewer
Location:
chromosome: I
Exon count:
10
Sequence:
Chromosome: I; NC_003279.8 (3798260..3805737, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SSD domain-containing protein Neighboring gene hypothetical protein Neighboring gene RING-type domain-containing protein Neighboring gene E3 ubiquitin-protein ligase ubr-1 Neighboring gene Nuclear Pore complex Protein

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
1-phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
1-phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
1-phosphatidylinositol binding ISS
Inferred from Sequence or Structural Similarity
more info
 
SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
clathrin binding IEA
Inferred from Electronic Annotation
more info
 
clathrin binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
clathrin heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol-4,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phospholipid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
clathrin coat assembly IEA
Inferred from Electronic Annotation
more info
 
clathrin-dependent endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endocytosis IEA
Inferred from Electronic Annotation
more info
 
locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of necrotic cell death IGI
Inferred from Genetic Interaction
more info
PubMed 
post-embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization to postsynaptic membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
receptor-mediated endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
regulation of receptor localization to synapse IDA
Inferred from Direct Assay
more info
PubMed 
synaptic vesicle budding from presynaptic endocytic zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
vesicle budding from membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
clathrin-coated pit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
clathrin-coated pit IDA
Inferred from Direct Assay
more info
PubMed 
clathrin-coated pit IEA
Inferred from Electronic Annotation
more info
 
clathrin-coated vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
clathrin-coated vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
extrinsic component of presynaptic endocytic zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
presynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
presynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Phosphatidylinositol-binding clathrin assembly protein unc-11
NP_001021014.1
  • Confirmed by transcript evidence
NP_001021015.1
  • Confirmed by transcript evidence
NP_001021016.1
  • Confirmed by transcript evidence
NP_491227.1
  • Confirmed by transcript evidence
NP_491228.1
  • Partially confirmed by transcript evidence
NP_491229.1
  • Partially confirmed by transcript evidence
NP_491230.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3798260..3805737 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001025843.3NP_001021014.1  Phosphatidylinositol-binding clathrin assembly protein unc-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021014.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZI6
    Conserved Domains (1) summary
    cl02544
    Location:37299
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
  2. NM_001025845.3NP_001021016.1  Phosphatidylinositol-binding clathrin assembly protein unc-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021016.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZI6
    Conserved Domains (1) summary
    cl02544
    Location:37299
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
  3. NM_058826.2NP_491227.1  Phosphatidylinositol-binding clathrin assembly protein unc-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491227.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZI6
    Conserved Domains (1) summary
    cl02544
    Location:37299
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
  4. NM_058829.4NP_491230.1  Phosphatidylinositol-binding clathrin assembly protein unc-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491230.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZI6
  5. NM_058828.2NP_491229.1  Phosphatidylinositol-binding clathrin assembly protein unc-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491229.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZI6
    Conserved Domains (1) summary
    cl02544
    Location:37299
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
  6. NM_058827.4NP_491228.1  Phosphatidylinositol-binding clathrin assembly protein unc-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491228.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZI6
    Conserved Domains (1) summary
    cl02544
    Location:37299
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
  7. NM_001025844.2NP_001021015.1  Phosphatidylinositol-binding clathrin assembly protein unc-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021015.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZI6
    Conserved Domains (1) summary
    cl02544
    Location:37299
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
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