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tppp-1 Tubulin polymerization-promoting protein homolog [ Caenorhabditis elegans ]

Gene ID: 171948, updated on 9-Dec-2024

Summary

Official Symbol
tppp-1
Official Full Name
Tubulin polymerization-promoting protein homolog
Primary source
WormBase:WBGene00016321
Locus tag
CELE_C32E8.3
See related
AllianceGenome:WB:WBGene00016321
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable tubulin binding activity. Predicted to be involved in microtubule bundle formation; microtubule polymerization; and positive regulation of protein polymerization. Predicted to colocalize with microtubule. Orthologous to human TPPP (tubulin polymerization promoting protein); TPPP2 (tubulin polymerization promoting protein family member 2); and TPPP3 (tubulin polymerization promoting protein family member 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See tppp-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (3786588..3787496)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene FHA domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Large ribosomal subunit protein eL13 Neighboring gene SSD domain-containing protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tubulin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in microtubule bundle formation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in microtubule polymerization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in microtubule polymerization IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of protein polymerization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
colocalizes_with microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Tubulin polymerization-promoting protein homolog
NP_491219.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3786588..3787496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058818.4NP_491219.1  Tubulin polymerization-promoting protein homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491219.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91127
    Conserved Domains (1) summary
    pfam05517
    Location:18175
    p25-alpha; p25-alpha