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aatf-1 Protein BFR2 [ Caenorhabditis elegans ]

Gene ID: 171723, updated on 2-Dec-2025
Official Symbol
aatf-1
Official Full Name
Protein BFR2
Primary source
WormBase:WBGene00022269
Locus tag
CELE_Y73E7A.2
See related
AllianceGenome:WB:WBGene00022269
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in nucleus. Predicted to be active in nucleolus. Orthologous to human AATF (apoptosis antagonizing transcription factor). [provided by Alliance of Genome Resources, Jul 2025]
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Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (1601838..1606846)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Putative complexin-1 Neighboring gene pseudo Neighboring gene Bladder cancer-associated protein Neighboring gene WD and tetratricopeptide repeats protein 1;WD_REPEATS_REGION domain-containing protein Neighboring gene Beta-1,4-N-acetylgalactosaminyltransferase bre-4

Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation. Itani OA, et al. Curr Biol, 2021 Jan 11. PMID 33157031, Free PMC Article
  2. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
  3. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
  4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
Protein BFR2
NP_490870.2
  • Confirmed by transcript evidence

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    1601838..1606846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058469.9 → NP_490870.2  Protein BFR2

    See identical proteins and their annotated locations for NP_490870.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9GUM5
    Conserved Domains (2) summary
    pfam08164
    Location:375 → 462
    TRAUB; Apoptosis-antagonizing transcription factor, C-terminal
    pfam13339
    Location:142 → 303
    AATF-Che1; Apoptosis antagonizing transcription factor
Nucleotide Protein
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