U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

acs-13 Long-chain-fatty-acid--CoA ligase [ Caenorhabditis elegans ]

Gene ID: 171643, updated on 18-Sep-2024

Summary

Official Symbol
acs-13
Official Full Name
Long-chain-fatty-acid--CoA ligase
Primary source
WormBase:WBGene00022037
Locus tag
CELE_Y65B4BL.5
See related
AllianceGenome:WB:WBGene00022037
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be active in endoplasmic reticulum and membrane. Is expressed in body wall musculature; head; hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in acute myeloid leukemia and leukemia. Orthologous to several human genes including ACSL5 (acyl-CoA synthetase long chain family member 5). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See acs-13 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (511044..519646, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Dolichyl-phosphate-mannose--protein mannosyltransferase Neighboring gene P-granule-associated protein deps-1 Neighboring gene Transmembrane protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene (Na+)-NQR maturation NqrM Neighboring gene ncRNA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables long-chain fatty acid-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in long-chain fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Long-chain-fatty-acid--CoA ligase
NP_001293196.1
  • Confirmed by transcript evidence
NP_001368382.1
  • Confirmed by transcript evidence
NP_490744.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    511044..519646 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058343.5NP_490744.1  Long-chain-fatty-acid--CoA ligase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_490744.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N302
    Conserved Domains (1) summary
    cd05927
    Location:140716
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)
  2. NM_001306267.3NP_001293196.1  Long-chain-fatty-acid--CoA ligase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293196.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLI5
    Conserved Domains (1) summary
    cd05927
    Location:147723
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)
  3. NM_001379780.1NP_001368382.1  Long-chain-fatty-acid--CoA ligase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CK48
    Conserved Domains (1) summary
    cd05927
    Location:97673
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)