Format

Send to:

Choose Destination

Gpc2 glypican 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 171517, updated on 30-Sep-2021

Summary

Official Symbol
Gpc2provided by RGD
Official Full Name
glypican 2provided by RGD
Primary source
RGD:621363
See related
EnsemblRapid:ENSRNOG00000001367
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
heparan sulfate proteoglycan; may play a role with neural development [RGD, Feb 2006]
Expression
Biased expression in Lung (RPKM 12.2), Testes (RPKM 12.1) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Gpc2 in Genome Data Viewer
Location:
12q11
Exon count:
11
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (17277875..17284297, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (19593041..19599374, complement)

Chromosome 12 - NC_051347.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 14 Neighboring gene galactose-3-O-sulfotransferase 4 Neighboring gene stromal antigen 3 Neighboring gene PVR related immunoglobulin domain containing

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neuron differentiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of neuron projection development IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of protein localization to membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in smoothened signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in smoothened signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in anchored component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cellular_component ND
No biological Data available
more info
 
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular matrix TAS
Traceable Author Statement
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
glypican-2
Names
HSPG M13
cerebroglycan

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138511.2NP_612520.1  glypican-2 precursor

    See identical proteins and their annotated locations for NP_612520.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000225
    UniProtKB/Swiss-Prot
    P51653
    Related
    ENSRNOP00000001849.2, ENSRNOT00000001849.5
    Conserved Domains (1) summary
    pfam01153
    Location:22565
    Glypican; Glypican

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051347.1 Reference mRatBN7.2 Primary Assembly

    Range
    17277875..17284297 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089052.1XP_038944980.1  glypican-2 isoform X2

    Conserved Domains (1) summary
    pfam01153
    Location:1320
    Glypican
  2. XM_039089053.1XP_038944981.1  glypican-2 isoform X2

    Conserved Domains (1) summary
    pfam01153
    Location:1320
    Glypican
  3. XM_039089054.1XP_038944982.1  glypican-2 isoform X2

    Conserved Domains (1) summary
    pfam01153
    Location:1320
    Glypican
  4. XM_039089051.1XP_038944979.1  glypican-2 isoform X1

    Conserved Domains (1) summary
    pfam01153
    Location:22437
    Glypican
Support Center