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FAM9C family with sequence similarity 9 member C [ Homo sapiens (human) ]

Gene ID: 171484, updated on 5-Aug-2022

Summary

Official Symbol
FAM9Cprovided by HGNC
Official Full Name
family with sequence similarity 9 member Cprovided by HGNC
Primary source
HGNC:HGNC:18405
See related
Ensembl:ENSG00000187268 MIM:300479; AllianceGenome:HGNC:18405
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TEX39C
Summary
This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be localized to the nucleus as the protein contains several nuclear localization signals, and has similarity to a synaptonemal complex protein. [provided by RefSeq, Aug 2011]
Expression
Restricted expression toward spleen (RPKM 20.1) See more
Orthologs
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Genomic context

See FAM9C in Genome Data Viewer
Location:
Xp22.2
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (13035617..13044620, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (12617034..12626037, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (13053736..13062739, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chrX.239 Neighboring gene CRISPRi-validated cis-regulatory element chrX.240 Neighboring gene uncharacterized LOC105373133 Neighboring gene uncharacterized LOC105373134

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spermatid development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in synaptonemal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein FAM9C
Names
testis expressed 39C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021290.1 RefSeqGene

    Range
    5179..14182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_174901.6NP_777561.1  protein FAM9C

    See identical proteins and their annotated locations for NP_777561.1

    Status: VALIDATED

    Source sequence(s)
    AC139705, AF494345
    Consensus CDS
    CCDS35203.1
    UniProtKB/Swiss-Prot
    Q5HYJ6, Q8IZT9
    UniProtKB/TrEMBL
    A0A024RBW5
    Related
    ENSP00000369999.3, ENST00000380625.8
    Conserved Domains (1) summary
    pfam04803
    Location:78158
    Cor1; Cor1/Xlr/Xmr conserved region

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    13035617..13044620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005274460.4XP_005274517.1  protein FAM9C isoform X2

    See identical proteins and their annotated locations for XP_005274517.1

    UniProtKB/Swiss-Prot
    Q5HYJ6, Q8IZT9
    UniProtKB/TrEMBL
    A0A024RBW5
    Related
    ENSP00000334430.3, ENST00000333995.7
    Conserved Domains (1) summary
    pfam04803
    Location:78158
    Cor1; Cor1/Xlr/Xmr conserved region
  2. XM_024452348.2XP_024308116.2  protein FAM9C isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    12617034..12626037 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)