Format

Send to:

Choose Destination

FAM9B family with sequence similarity 9 member B [ Homo sapiens (human) ]

Gene ID: 171483, updated on 23-Nov-2021

Summary

Official Symbol
FAM9Bprovided by HGNC
Official Full Name
family with sequence similarity 9 member Bprovided by HGNC
Primary source
HGNC:HGNC:18404
See related
Ensembl:ENSG00000177138 MIM:300478
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TEX39B
Summary
This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be localized to the nucleus as the protein contains several nuclear localization signals, and has similarity to a synaptonemal complex protein. [provided by RefSeq, Aug 2011]
Expression
Biased expression in testis (RPKM 1.2), endometrium (RPKM 0.2) and 2 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See FAM9B in Genome Data Viewer
Location:
Xp22.31
Exon count:
10
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (9024232..9034127, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (8992273..9002168, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373125 Neighboring gene NOLC1 pseudogene 1 Neighboring gene RNA, 5S ribosomal pseudogene 499 Neighboring gene BRICK1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ40182

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spermatid development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
is_active_in synaptonemal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein FAM9B
Names
testis expressed 39B

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205849.3NP_995321.1  protein FAM9B

    See identical proteins and their annotated locations for NP_995321.1

    Status: VALIDATED

    Source sequence(s)
    AC074281, AF494344
    Consensus CDS
    CCDS14132.1
    UniProtKB/Swiss-Prot
    Q8IZU0
    UniProtKB/TrEMBL
    A0A024RBV3
    Related
    ENSP00000318716.5, ENST00000327220.10
    Conserved Domains (1) summary
    pfam04803
    Location:61186
    Cor1; Cor1/Xlr/Xmr conserved region

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    9024232..9034127 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024452346.1XP_024308114.1  protein FAM9B isoform X2

    Related
    ENSP00000498495.1, ENST00000651278.1
    Conserved Domains (1) summary
    pfam04803
    Location:61186
    Cor1; Cor1/Xlr/Xmr conserved region
  2. XM_024452345.1XP_024308113.1  protein FAM9B isoform X1

    Related
    ENSP00000412606.1, ENST00000428477.1
    Conserved Domains (1) summary
    pfam04803
    Location:106231
    Cor1; Cor1/Xlr/Xmr conserved region

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_173696.1: Suppressed sequence

    Description
    NM_173696.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
Support Center