U.S. flag

An official website of the United States government


Send to:

Choose Destination

FAM9B family with sequence similarity 9 member B [ Homo sapiens (human) ]

Gene ID: 171483, updated on 7-Apr-2024


Official Symbol
FAM9Bprovided by HGNC
Official Full Name
family with sequence similarity 9 member Bprovided by HGNC
Primary source
See related
Ensembl:ENSG00000177138 MIM:300478; AllianceGenome:HGNC:18404
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be localized to the nucleus as the protein contains several nuclear localization signals, and has similarity to a synaptonemal complex protein. [provided by RefSeq, Aug 2011]
Biased expression in testis (RPKM 1.2), endometrium (RPKM 0.2) and 2 other tissues See more
Try the new Gene table
Try the new Transcript table

Genomic context

See FAM9B in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (9024232..9034127, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (8591248..8601142, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (8992273..9002168, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 3114 Neighboring gene NOLC1 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29397 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:9098527-9099726 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:9102725-9103225 Neighboring gene RNA, 5S ribosomal pseudogene 499 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:9112116-9112640 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:9112641-9113166 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:9116815-9117320 Neighboring gene BRICK1 pseudogene 1

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018


EBI GWAS Catalog

Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.
EBI GWAS Catalog


Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • FLJ40182

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
Process Evidence Code Pubs
involved_in meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
involved_in spermatid development IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
is_active_in synaptonemal complex IBA
Inferred from Biological aspect of Ancestor
more info

General protein information

Preferred Names
protein FAM9B
testis expressed 39B

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205849.3NP_995321.1  protein FAM9B

    See identical proteins and their annotated locations for NP_995321.1

    Status: VALIDATED

    Source sequence(s)
    AC074281, AF494344
    Consensus CDS
    Q0IJ68, Q8IZU0, Q8N7Z8
    ENSP00000318716.5, ENST00000327220.10
    Conserved Domains (1) summary
    Cor1; Cor1/Xlr/Xmr conserved region

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    9024232..9034127 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047441882.1XP_047297838.1  protein FAM9B isoform X1

Alternate T2T-CHM13v2.0


  1. NC_060947.1 Alternate T2T-CHM13v2.0

    8591248..8601142 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054326600.1XP_054182575.1  protein FAM9B isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_173696.1: Suppressed sequence

    NM_173696.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.