Mageb3 MAGE family member B3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mageb3provided by MGI
Official Full Name: MAGE family member B3provided by MGI
Primary source: MGI:MGI:105109
See related: Ensembl:ENSMUSG00000074881 AllianceGenome:MGI:105109
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Smage3; Mage-b3; Mage-ps1; Mage-rs3
Summary: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including brain; egg cylinder; heart; liver; and reproductive system. Orthologous to human MAGEB6 (MAGE family member B6). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 2; 2 E5

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (121784252..121786573, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (121953771..121956092, complement)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

mammary tumor expression of mage-b3 TAA has been demonstrated
Title: Potential mouse tumor model for pre-clinical testing of mage-specific breast cancer vaccines.

Submit: New GeneRIF Correction

General gene information

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Markers

Mageb1 (e-PCR), detects polymorphism
- UniSTS:546557

Homology

Homologs of the Mageb3 gene: The Mageb3 gene is conserved in human, chimpanzee, Rhesus monkey, and dog.
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

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Preferred Names: melanoma antigen family B, 3

Names: melanoma antigen, family B, 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.