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ZNF675 zinc finger protein 675 [ Homo sapiens (human) ]

Gene ID: 171392, updated on 23-Nov-2021

Summary

Official Symbol
ZNF675provided by HGNC
Official Full Name
zinc finger protein 675provided by HGNC
Primary source
HGNC:HGNC:30768
See related
Ensembl:ENSG00000197372
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TIZ; TBZF
Expression
Ubiquitous expression in lymph node (RPKM 3.0), testis (RPKM 2.9) and 24 other tissues See more
Orthologs
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Genomic context

See ZNF675 in Genome Data Viewer
Location:
19p12
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (23652801..23687212, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (23835603..23870014, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein S27 pseudogene 29 Neighboring gene vomeronasal 1 receptor 93 pseudogene Neighboring gene vomeronasal 1 receptor 94 pseudogene Neighboring gene zinc finger protein 681 Neighboring gene ribosomal protein SA pseudogene 58 Neighboring gene BCL2 interacting protein 3 pseudogene 39

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ36350

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding NAS
Non-traceable Author Statement
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin protein ligase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables zinc ion binding NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 675
Names
TRAF6 inhibitory zinc finger
TRAF6-binding zinc finger protein
TRAF6-inhibitory zinc finger protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138330.3NP_612203.2  zinc finger protein 675

    See identical proteins and their annotated locations for NP_612203.2

    Status: VALIDATED

    Source sequence(s)
    AC073544, DA777369
    Consensus CDS
    CCDS32981.1
    UniProtKB/Swiss-Prot
    Q8TD23
    Related
    ENSP00000352836.3, ENST00000359788.9
    Conserved Domains (6) summary
    smart00349
    Location:462
    KRAB; krueppel associated box
    COG5048
    Location:169556
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:314334
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:174194
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:494519
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    23652801..23687212 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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