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Myo9a myosin IXA [ Rattus norvegicus (Norway rat) ]

Gene ID: 171296, updated on 18-Aug-2021

Summary

Official Symbol
Myo9aprovided by RGD
Official Full Name
myosin IXAprovided by RGD
Primary source
RGD:621395
See related
Ensembl:ENSRNOG00000011619
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
myr 7
Summary
human homolog is an unconventional myosin and may be associated with Bardet-Biedl syndrome [RGD, Feb 2006]
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Kidney (RPKM 287.8), Lung (RPKM 217.1) and 9 other tissues See more
Orthologs
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Genomic context

See Myo9a in Genome Data Viewer
Location:
8q24
Exon count:
44
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (60149234..60348726)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (64573248..64777607)

Chromosome 8 - NC_051343.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094178 Neighboring gene GRAM domain containing 2A Neighboring gene 40S ribosomal protein S15a pseudogene Neighboring gene thymosin beta-10-like Neighboring gene SUMO peptidase family member, NEDD8 specific Neighboring gene uncharacterized LOC102546766 Neighboring gene nuclear receptor subfamily 2, group E, member 3 Neighboring gene thrombospondin type 1 domain containing 4 Neighboring gene uncharacterized LOC120094180

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in cell junction assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in cell junction assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in cell junction assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in establishment of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 
involved_in establishment of epithelial cell apical/basal polarity ISO
Inferred from Sequence Orthology
more info
 
involved_in establishment of epithelial cell apical/basal polarity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of neuron projection arborization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of neuron projection arborization ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in axonal growth cone ISO
Inferred from Sequence Orthology
more info
 
located_in axonal growth cone ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in cellular_component ND
No biological Data available
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
unconventional myosin-IXa
Names
myosin-IXa
unconventional myosin-9a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134335.2NP_599162.2  unconventional myosin-IXa

    Status: VALIDATED

    Source sequence(s)
    JACYVU010000198
    Related
    ENSRNOP00000015963.6, ENSRNOT00000015963.6
    Conserved Domains (5) summary
    smart00015
    Location:11151137
    IQ; Calmodulin-binding motif
    cd04406
    Location:21292314
    RhoGAP_myosin_IXA; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in myosins IXA. Class IX myosins contain a characteristic head domain, a neck domain and a tail domain which contains a C6H2-zinc binding motif and a Rho-GAP domain. Class ...
    cd01385
    Location:1601005
    MYSc_Myo9; class IX myosin, motor domain
    cd17216
    Location:15110
    RA_Myosin-IXa; Ras-associating (RA) domain found in Myosin-IXa
    cd20883
    Location:20632120
    C1_Myosin-IXa; protein kinase C conserved region 1 (C1 domain) found in unconventional myosin-IXa and similar proteins

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051343.1 Reference mRatBN7.2 Primary Assembly

    Range
    60149234..60348726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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