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Marcks myristoylated alanine rich protein kinase C substrate [ Mus musculus (house mouse) ]

Gene ID: 17118, updated on 5-Sep-2021

Summary

Official Symbol
Marcksprovided by MGI
Official Full Name
myristoylated alanine rich protein kinase C substrateprovided by MGI
Primary source
MGI:MGI:96907
See related
Ensembl:ENSMUSG00000069662
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ma; Macs; PKCSL
Expression
Broad expression in CNS E11.5 (RPKM 127.7), whole brain E14.5 (RPKM 108.5) and 22 other tissues See more
Orthologs
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Genomic context

See Marcks in Genome Data Viewer
Location:
10 B1; 10 19.49 cM
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (37009239..37014922, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (37133243..37138926, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (36853049..36858732, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene heparan sulfate (glucosamine) 3-O-sulfotransferase 5 Neighboring gene predicted gene, 22554 Neighboring gene histone deacetylase 2 Neighboring gene RIKEN cDNA 5930403N24 gene Neighboring gene predicted gene, 26535 Neighboring gene predicted gene, 31202

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables actin filament binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables calmodulin binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphatidylserine binding ISO
Inferred from Sequence Orthology
more info
 
enables phospholipid binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase C binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in actin filament bundle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in actin filament bundle IDA
Inferred from Direct Assay
more info
PubMed 
located_in axon terminus ISO
Inferred from Sequence Orthology
more info
 
located_in bleb ISO
Inferred from Sequence Orthology
more info
 
located_in cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromatoid body ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in dendritic branch ISO
Inferred from Sequence Orthology
more info
 
located_in dendritic spine ISO
Inferred from Sequence Orthology
more info
 
located_in germinal vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in growth cone ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in outer dense fiber ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
myristoylated alanine-rich C-kinase substrate
Names
80K protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008538.2NP_032564.1  myristoylated alanine-rich C-kinase substrate

    See identical proteins and their annotated locations for NP_032564.1

    Status: VALIDATED

    Source sequence(s)
    AC133944, BB569984, BC046601, M60474
    Consensus CDS
    CCDS23784.1
    UniProtKB/Swiss-Prot
    P26645
    Related
    ENSMUSP00000090245.6, ENSMUST00000092584.6
    Conserved Domains (1) summary
    pfam02063
    Location:2305
    MARCKS; MARCKS family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    37009239..37014922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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