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Amacr alpha-methylacyl-CoA racemase [ Mus musculus (house mouse) ]

Gene ID: 17117, updated on 31-Jan-2019

Summary

Official Symbol
Amacrprovided by MGI
Official Full Name
alpha-methylacyl-CoA racemaseprovided by MGI
Primary source
MGI:MGI:1098273
See related
Ensembl:ENSMUSG00000022244
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Macr1
Expression
Broad expression in liver adult (RPKM 25.9), kidney adult (RPKM 22.2) and 25 other tissues See more
Orthologs

Genomic context

See Amacr in Genome Data Viewer
Location:
15; 15 A1
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (10981756..10996624)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (10911511..10926379)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 29742 Neighboring gene predicted gene, 34315 Neighboring gene C1q and tumor necrosis factor related protein 3 Neighboring gene solute carrier family 45, member 2 Neighboring gene relaxin family peptide receptor 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
alpha-methylacyl-CoA racemase activity ISO
Inferred from Sequence Orthology
more info
 
alpha-methylacyl-CoA racemase activity TAS
Traceable Author Statement
more info
PubMed 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
isomerase activity IEA
Inferred from Electronic Annotation
more info
 
signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
bile acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
bile acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
isoprenoid catabolic process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
mitochondrion HDA PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
peroxisome ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
alpha-methylacyl-CoA racemase
Names
2-arylpropionyl-CoA epimerase
2-methylacyl-CoA racemase
alpha-methylacyl-Coenzyme A racemase
NP_032563.2
XP_011243640.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008537.4NP_032563.2  alpha-methylacyl-CoA racemase

    See identical proteins and their annotated locations for NP_032563.2

    Status: VALIDATED

    Source sequence(s)
    AK048249
    Consensus CDS
    CCDS27381.1
    UniProtKB/Swiss-Prot
    O09174
    Related
    ENSMUSP00000066915.5, ENSMUST00000070877.6
    Conserved Domains (1) summary
    COG1804
    Location:3372
    CaiB; Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid transport and metabolism]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

    Range
    10981756..10996624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245338.1XP_011243640.1  alpha-methylacyl-CoA racemase isoform X1

    Conserved Domains (1) summary
    COG1804
    Location:1215
    CaiB; Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid transport and metabolism]
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